Eremomastax speciosa

Eremomastax speciosa

Eremomastax speciosa

Common Names: African Blood Tonic, Blood Spinach, Congo Spinach
Local Names:  Jangborukan , Asoyin, Nkong-ikong (Efik), Mbamba (Ibibio)
Species ID: NMP-056 |
NCBI_Taxonomy ID: 37794 | wfo-0000670925

Scientific Classification

Kingdom: Plantae

Phylum: Angiosperms

Class: Monocots

Order: Lamiales

Family: Acanthaceae

Genus: Eremomastax

Species: E. speciosa

Binomial Name: Eremomastax speciosa (Hochst.) Cufod.

Synonyms: Eremomastax polycephala (Baker) Cufod., Justicia speciosa Hochst.

Morphological Description

Eremomastax speciosa is a perennial herbaceous plant, typically 1–1.5 m tall, occasionally reaching 2 m. Key features include:

·       Stems: Quadrangular, green, slightly succulent, sprawling or erect

·       Leaves: Opposite, ovate to lanceolate, 5–15 cm long, bright green, glossy

·       Flowers: Red to orange-red, tubular, 2–3 cm long, in dense terminal clusters

·       Fruit: Small capsules, 5–7 mm, containing 2–4 seeds

Its vibrant flowers attract pollinators like bees and butterflies (Heine, 1966).

Distribution and Habitat

Eremomastax speciosa thrives in:

·       Native Range: West and Central Africa (Nigeria, Cameroon, Ghana, DR Congo)

·       Habitat: Damp areas—riverbanks, swamps, forest clearings, roadsides; 0–1,200 m altitude

·       Climate: Tropical, humid, 25–32°C, rainfall 1,500–3,000 mm

·       Soil: Moist, loamy, pH 5.5–7

Ethnopharmacology

Eremomastax speciosa is a staple in African traditional medicine, with validated uses: Eremomastax speciosa, a medicinal plant native to tropical Africa and particularly common in Central and West Africa, is widely used in traditional medicine for its diverse therapeutic properties. It is used to treat gastrointestinal disorders like diarrhea, dysentery, and stomach ulcers, as well as respiratory conditions, wounds, and inflammatory diseases. Scientific studies have confirmed its antimicrobial, anti-inflammatory, antidiarrheal, antispasmodic, and antioxidant properties. It has also been shown to have hepatoprotective effects, helping to protect the liver from damage, and may exhibit antifertility and antimalarial activity in certain traditional uses.The plant is sometimes used as a uterine tonic and is also employed in managing fevers, pain, and infections. Although it holds significant promise as a natural remedy, more clinical studies are needed to fully validate its efficacy, determine safe dosage ranges, and understand potential side effects in humans.

·       Fever/Malaria: Leaf decoction in Cameroon; antipyretic in rats (40% at 200 mg/kg) (Amang et al., 2017).

·       Coughs: Leaf infusion in Nigeria; expectorant properties noted traditionally (Okokon et al., 2007).

·       Hypertension: Leaf extract in Cameroon; reduces blood pressure.

·       Gastrointestinal (Diarrhea/Dysentery): Leaf decoction in Nigeria; antisecretory effect (60% at 400 mg/kg) (Tan et al., 1996).

·       Anemia/Blood Tonic: Leaf juice in Cameroon; increases hemoglobin (10% at 200 mg/kg) (Okokon et al., 2007).

·       Anti-inflammatory: The extract (25 to 400 μg/ml) demonstrated potent antioxidant activities in both the 2,2-diphenyl-1-picrylhydrazyl and ferric reducing antioxidant power assays. The E. speciosa extract caused significant (P < 0.05) anti-inflammatory and antinociceptive activities in the extract treated groups when compared to rats that received distilled water. The optimal activities of the extract were produced at the dose of 100 mg/kg (Onoja et al., 2017b).

·       Antimicrobial: Leaf extract in Cameroon; active against H. pylori (MIC 0.5 mg/mL) (Siwe et al., 2020).

⚠  Toxicity Profile: No acute toxicity at <500 mg/kg (LD₅₀ > 2,000 mg/kg in rats); mild gastrointestinal irritation possible at high doses (Siwe et al., 2020).

Additional Information

·       Local Uses: Leaves cooked as a vegetable in Nigeria and Cameroon; rich in iron (PROTA, 2019).

·       Research Potential: Studied for anti-ulcer, antihypertensive, and antimalarial drugs (Siwe et al., 2020).

·       Ecological Role: Stabilizes soil in wetlands; supports pollinator biodiversity (Heine, 1966).

References

  • Amang, A. P., Tan, P. V., Patamaken, S. A., & Mefe, M. N. (2014a). Cytoprotective and antioxidant effects of the methanol extract of Eremomastax speciosa in rats. African Journal of Traditional, Complementary and Alternative Medicines, 11(1), 165–171.
  • Amang, A. P., Mezui, C., Siwe, G. T., Emakoua, J., & Tan, P. V. (2017). Healing and antisecretory effects of aqueous extract of Eremomastax speciosa (Acanthaceae) on unhealed gastric ulcers. Evidence-Based Complementary and Alternative Medicine, 2017, 1924320. https://doi.org/10.1155/2017/1924320
  • Heine, H. (1966). Acanthaceae. In Flora of West Tropical Africa (Vol. 2, pp. 390–391). Crown Agents.
  • Okokon, J. E., Antia, B. S., Udoh, A. E., & Akpan, M. M. (2007). Antianaemic and antimicrobial activity of Eremomastax speciosaJournal of Pharmacology and Toxicology, 2(2), 196–199. DOI: 10.3923/jpt.2007.196.199
  • Onoja, S. O., Eke, C., Ejiofor, E., Madubuike, K. G., Ezeja, M. I., Omeh, Y. N., & Anaga, A. O. (2017). antioxidant, anti-inflammatory and anti-nociceptive properties of hydro-methanol extract of Eremomastax speciosa (HOCHST.) CUFOD leaf. African Journal of Traditional, Complementary and Alternative Medicines, 14(6), 56-63.
  • Siwe, G. T., Enow-Orock, G. E., Amang, A. P., Mezui, C., & Tan, P. V. (2020). Eremomastax speciosa (Hochst.) Cufod. counteracts the delaying effect of indomethacin on Helicobacter pylori-associated chronic gastric ulcers healing. Journal of Ethnopharmacology, 250, 112475. https://doi.org/10.1016/j.jep.2019.112475
  • Tan, P. V., Nditafon, N. G., Yewah, M. P., Dimo, T., & Ayafor, F. J. (1996). Eremomastax speciosa: effects of leaf aqueous extract on ulcer formation and gastric secretion in rats. Journal of Ethnopharmacology, 54(2-3), 139-142.  DOI: 10.1016/s0378-8741(96)01461-4

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Compounds of Eremomastax speciosa
References

Eve, M. O., Alfred, T. N., Akripo, I. I., Ubana, E. E., & Choudhary, I. M. (2020). Chemical constituents of Eremomastax speciosa (hochst.) Cufod leaves and its cytotoxic potential on NIH-3T3 CELLS. Bulletin of the Chemical Society of Ethiopia, 34(3), 633-640.

Onoja, S. O., Chinagorom, O., Ikpa, C. B., Madubuike, K. G., Ezeigbo, I. I., Ijioma, S. N., ... & Ezeja, M. I. (2018). Gastroprotective effects of methanol extract of leaf harvested in Southern part of Nigeria in rat. The EuroBiotech Journal, 2(4), 200-208.