Artocarpus altilis.

Artocarpus altilis.

Artocarpus altilis

Common Names: Breadfruit, Breadnut, Ulu
Local Names: Berefurutu (Yoruba, Nigeria), Gwandar daji (Hausa, Nigeria), Jaloke (Nigeria), Sukun (Malay, Indonesia), Rimas (Tagalog, Philippines), Kamansi (Visayan, Philippines), Mkonokono (Swahili, East Africa)
Species ID: NMP-010 |
wfo-0000550425, NCBI:txid194251

Scientific Classification

Kingdom: Plantae

Phylum: Tracheophyta

Class: Magnoliopsida

Order: Rosales

Family: Moraceae

Genus: Artocarpus

Species: A. altilis

Synonyms: Artocarpus altilis var. non-seminiferus (Duss) Fournet, Artocarpus altilis var. seminiferus (Duss) Fournet, Artocarpus communis J.R.Forst. & G.Forst., Artocarpus incisifolius Stokes, Artocarpus incisus (Thunb.) L.f., Artocarpus laevis Hassk., Artocarpus papuanus Diels, Artocarpus rima Blanco, Radermachia incisa Thunb., Saccus laevis Kuntze, Sitodium altile Parkinson ex F.A.Zorn

Morphological Description

Artocarpus altilis, commonly known as breadfruit, is a large evergreen tree, typically growing 15–30 m tall, with a broad, spreading canopy up to 20 m wide. Its key features include:

·       Stem: Trunk straight, up to 1 m in diameter, with greyish-brown bark exuding white latex when cut

·       Leaves: Large, alternate, deeply lobed, 20–90 cm long, 20–50 cm wide, glossy dark green, leathery, with pubescent undersides

·       Flowers: Monoecious, with male flowers in cylindrical spikes (15–25 cm long) and female flowers in globular heads

·       Fruit: Round to oblong, 10–30 cm in diameter, 0.5–2 kg, green to yellowish, with smooth, warty, or spiky skin; starchy white flesh, bread-like when cooked

Distribution and Habitat

Artocarpus altilis likely originated in New Guinea and the Indo-Malay region, domesticated in Polynesia from the seeded *Artocarpus camansi*. Spread by Austronesian voyagers 3,000 years ago, it reached Oceania, and European colonial efforts in the 18th century introduced it to the Caribbean, Central America, Africa, and Southeast Asia. It is now cultivated in over 90 countries, including Nigeria, Ghana, and the Philippines. It thrives in:

·       Ecosystems: Tropical forests, coastal lowlands, and cultivated plantations

·       Climate: Tropical, with rainfall of 1,500–3,000 mm annually and temperatures of 21–32°C

·       Soils: Well-drained, fertile, loamy to sandy, pH 6.0–7.5

·       Altitude: Sea level to 1,500 m

In Nigeria, it is grown in southern states like Ogun and Delta, often in mixed agroforestry systems.

Ethnopharmacology

Artocarpus altilis, commonly known as breadfruit, is a medicinal and nutritional plant traditionally used in tropical regions. Various parts of the plant—including the leaves, fruits, bark, and latex—are known for their antimicrobial, anti-inflammatory, antioxidant, antidiabetic, and wound-healing properties. Traditionally, leaf extracts are used to manage high blood pressure, diabetes, liver disorders, and skin infections, while the latex is applied to treat skin wounds, fungal infections, and inflammations. The fruit itself is highly nutritious and often used to boost digestive health and support immune function. Phytochemical studies have identified active compounds such as flavonoids, tannins, phenolic compounds, and terpenoids, which contribute to its medicinal effects. While Artocarpus altilis is valued for both its health benefits and nutritional richness, more clinical studies are needed to comprehensively validate its therapeutic applications and determine standardized dosages.

·       Antioxidant Activity: Extracts from Artocarpus altilis have demonstrated significant antioxidant properties, attributed to the presence of phenolic compounds such as flavonoids. These compounds help in scavenging free radicals and reducing oxidative stress (Soifoini et al., 2021).

·       Antimicrobial Activity: Studies have shownongoing conversation that A. altilis extracts possess antimicrobial properties against various bacterial and fungal pathogens, supporting its traditional use in treating infections (Raju et al., 2017).

·       Anti-inflammatory Activity: Ethanol extracts of A. altilis leaves exhibited anti-inflammatory effects by inhibiting the production of pro-inflammatory mediators in LPS-induced RAW 264.7 cells (Fitrya et al., 2023).

·       Cytotoxic Activity: Methanol extracts of A. altilis fruit showed cytotoxic effects against MCF-7 breast cancer cells, indicating potential anticancer properties (Jalal et al., 2022).

·       Cardioprotective Effects: Aqueous leaf extracts reduced heart rate and infarct size in isoproterenol-induced myocardial injury in rats, validating their use for hypertension and heart conditions in Jamaica (Nwokocha et al., 2017;).

·       Insect Repellent and Antiparasitic: Crushed leaves repelled mosquitoes.

·       Photoprotective Effects: Heartwood extracts containing artocarpin suppressed UVB-induced skin damage in mice by reducing MMP-1 and pro-inflammatory cytokines (TNF-α, IL-6), validating their use for skin disorders in Southeast Asia (Tiraravesit et al., 2015;).

⚠  Toxicity Profile: Artocarpus altilis is generally safe when cooked, but raw fruit may cause nausea and bloating due to high starch content. The milky latex can cause contact dermatitis in sensitive individuals. Toxicological evaluations have indicated that A. altilis extracts are generally safe. In acute toxicity studies, no mortality or significant toxic reactions were observed in experimental animals at doses up to 2000 mg/kg body weight (Sairam & Urooj, 2014).

Additional Uses

·       Culinary: The starchy fruit is roasted, boiled, fried, or processed into flour, chips, or fermented products like poi in Hawaii and ginataang rimas in the Philippines. Seeds are roasted as snacks in Nigeria.

·       Timber: The lightweight, termite-resistant wood is used for construction, furniture, and canoe building in Polynesia and Nigeria.

·       Agroforestry: The tree’s canopy provides shade for crops like cocoa, and its roots stabilize soil in Caribbean plantations.

·       Animal Feed: Leaves and overripe fruits are used as fodder for livestock in Ghana.

References

  • Fitrya, Muharni, Wahyuni, F. S., & Amriani, A. (2023). Cytotoxicity and anti-inflammatory activity of ethanol extract of Artocarpus altilis (Parkinson ex F.A.Zorn) Fosberg leaf in lipopolysaccharide-stimulated RAW 264.7 cells. Journal of Pharmacy & Pharmacognosy Research, 11(3), 517–522. https://doi.org/10.56499/jppres23.1623_11.3.517
  • Jalal, T., Natto, H. A., & Wahab, R. A. (2022). Cytotoxicity and toxicological studies of Artocarpus altilis extracts, inducing apoptosis and cell cycle arrest via CASPASE-3 and CASPASE-8 pathways against human breast MCF-7 cells. Combinatorial Chemistry & High Throughput Screening, 25(6), 973–985.
  • Nwokocha, C. R., et al. (2017). Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol-induced myocardial damage in rats: Negative chronotropic and inotropic effects. Journal of Ethnopharmacology, 203, 163–170.
  • Raju, V., Bell, J. J., Merlin, N. J., & Dharan, S. S. (2017). Ethno pharmacological uses of Artocarpus altilis—A review. Asian Journal of Pharmaceutical Research, 7(4), 239–243.
  • Sairam, S., & Urooj, A. (2014). Safety evaluation of Artocarpus altilis as pharmaceutical agent in Wistar rats. Journal of Toxicology, 2014(1), 980404.
  • Soifoini, T., Donno, D., Jeannoda, V., Rakoto, D. D., Msahazi, A., Farhat, S. M. M., ... & Beccaro, G. L. (2021). Phytochemical composition, antibacterial activity, and antioxidant properties of the Artocarpus altilis fruits to promote their consumption in the Comoros Islands as potential health-promoting food or a source of bioactive molecules for the food industry. Foods, 10(9), 2136.
  • Tiraravesit, N., Yakaew, S., Rukchay, R., Luangpraditkun, K., Viennet, C., Humbert, P., & Viyoch, J. (2015). Artocarpus altilis heartwood extract protects skin against UVB in vitro and in vivo. Journal of Ethnopharmacology, 175, 153–162.

External Links

More Pictures

 

Compounds of Artocarpus altilis.
References


Mainasara, M. M., Bakar, M. F. A., & Barau, A. I. (2019). GC-MS analysis of phytochemical constituents from ethyl acetate and methanol extract of Artocarpus altilis (Parkinson) Fosberg from Endau Rompin, Johor, Malaysia. Traektoriâ Nauki= Path of Science, 5(5), 3001-3010.