Securidata longependuculat

Securidata longependuculat

Securidaca longepedunculata

Common Names: Violet tree, Rhodesian violet, Fibre tree, Wild wisteria, Senega root tree
Local Names: Uwar magunguna, Sanya (Hausa, Nigeria), Ipeta (Yoruba, Nigeria), Uturukpa (Igbo, Nigeria), Krinkhout (Afrikaans, South Africa), Satene (Bambara, Mali),
Species ID: NMP-267 |
wfo-0000503535

Scientific Classification

Kingdom: Plantae

Clade: Tracheophytes

Clade: Angiosperms

Clade: Eudicots

Clade: Rosids

Order: Fabales

Family: Polygalaceae

Genus: Securidaca

Species: S. longepedunculata

Synonyms: Lophostylis angustifolia Hochst., Lophostylis oblongifolia Hochst., Lophostylis pallida Klotzsch, Securidaca angustifolia Miq., Elsota longipedunculata (Fresen.) Kuntze

Morphological Description

Securidaca longepedunculata is a semi-deciduous shrub or small tree, typically 2–6 meters tall, occasionally reaching 12 meters, with an open, spreading crown. Its key characteristics include:

·       Bark: Young twigs yellow-green, maturing to rough, grey, stringy, flaking to reveal yellow beneath; used medicinally and as a pesticide (Burkill, 1985).

·       Leaves: Alternate, thin, oblong to lanceolate (2–5 cm × 0.5–2 cm), initially hairy, becoming glabrous; crowded at stem tips

·       Flowers: Small (1 cm), pink to purple, sweet-scented, in short axillary or terminal racemes on long peduncles (3–15 cm); bloom early summer (Prance & Jongkind, 2015).

·       Fruit: Round nut (1–1.5 cm), attached to a membranous wing (up to 4 cm), purple when young, beige when mature; fruiting April–August (Kew Science, n.d.).

Distribution and Habitat

Securidaca longepedunculata is widespread across sub-Saharan Africa, adapting to diverse environments:

·       Geographic Range: Found from Senegal to Ethiopia, south to South Africa; prevalent in northern Nigeria (Sokoto, Borno, Gombe) and southern Nigeria (Cross River); also in Kenya, Mali, Zambia, and Zimbabwe (Kew Science, n.d.).

·       Habitat: Thrives in savannas, woodlands, Sahel regions, and forest edges; prefers sandy, acidic, or rocky soils (pH 4.5–6.5) with 500–1,500 mm annual rainfall; occurs at elevations up to 2,000 m.

·       Ecological Role: Supports pollinators like butterflies; fruits dispersed by wind; used in agroforestry for soil conservation (Burkill, 1985).

Ethnopharmacology

Securidaca longepedunculata is a cornerstone of African traditional medicine, known as “Uwar magunguna” (mother of medicines) in Hausa, with extensive ethnopharmacological validation (Mongalo et al., 2015):

·       Anticancer: In Nigeria, root bark treats cancers. Ethanol root bark extract inhibited U87 brain tumor cell proliferation (IC50: 20.5 µg/mL) by inducing apoptosis via PARP cleavage, supporting its use against Ehrlich ascites carcinoma (Lawal et al., 2012).

·       Antitrypanosomal: Root bark treats sleeping sickness in Nigeria.

·       Antidiabetic: In Nigeria, roots manage diabetes

 

·       Anticonvulsant: Root extracts treat epilepsy in Nigeria. Aqueous root extract (400 mg/kg) delayed strychnine- and picrotoxin-induced seizures in mice, with effects partially reversed by naloxone, indicating opioid receptor involvement (Adeyemi et al., 2010).

·       Analgesic and Anti-inflammatory: Roots relieve pain and arthritis in Nigeria. Aqueous root extract (200–400 mg/kg) reduced acetic acid-induced nociception by 50% and formalin-induced inflammation in mice, linked to methyl salicylate (90% of root volatiles) (Ojewole, 2008).

·       Aphrodisiac: Root bark treats erectile dysfunction in Nigeria. Two xanthones (1,7-dimethoxy-2-hydroxyxanthone, 1,4-dihydroxy-7-methoxyxanthone) relaxed corpus cavernosal smooth muscle by 97% at 1.8 × 10⁻⁵ mg/mL, comparable to sildenafil (Meyer et al., 2006).

·       Antitubercular: In Mozambique, roots treat tuberculosis. n-Hexane root extracts showed antimycobacterial activity against Mycobacterium tuberculosis H37Ra (MIC: 15.6 µg/mL), suggesting potential anti-TB drug leads (Luo et al., 2011).

⚠  Toxicity Profile: Securidaca longepedunculata is potent and potentially toxic if misused. Roots contain methyl salicylate and xanthones, which can cause gastrointestinal distress or neurological symptoms at high doses. Acute toxicity studies showed no mortality at 2,000 mg/kg aqueous root extract in mice, but chronic use may elevate liver enzymes (ALT increased by 10%). Used traditionally as arrow poison, indicating high toxicity. Contraindicated in pregnancy, for children, and without expert supervision. Skin contact with extracts may cause irritation (Mongalo et al., 2015).

Additional Uses

·       Pesticidal: In Nigeria, powdered roots protect stored grains, achieving 100% mortality of weevils like Sitophilus zeamais after 6 days (Jayasekara et al., 2005).

·       Cultural: In Hausa culture, roots are used in rituals for spiritual protection; applied to pomades to ward off bewitchment (Burkill, 1985).

·       Timber and Fibre: Bark yields strong fibre (buaze) for cordage; wood used for small tools and fuel (Burkill, 1985).

·       Ecological: Enhances biodiversity in savannas, attracting birds and butterflies; used in agroforestry for soil stabilization.

References

  • Adeyemi, O. O., Yemitan, O. K., & Adebiyi, O. A. (2010). Anticonvulsant, anxiolytic and sedative activities of the aqueous root extract of Securidaca longepedunculata Fresen. Journal of Ethnopharmacology, 130(2), 191–195.
  • Burkill, H. M. (1985). The useful plants of West Tropical Africa (Vol. 4). Royal Botanic Gardens, Kew.
  • Jayasekara, T. K., Stevenson, P. C., Hall, D. R., & Belmain, S. R. (2005). Effect of volatile constituents from Securidaca longepedunculata on insect pests of stored grain. Journal of Chemical Ecology, 31(2), 303–313.
  • Kew Science. (n.d.). Securidaca longepedunculata Fresen. Plants of the World Online. https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:692714-1
  • Lawal,R. A. and Ozaslan,M. D. and Odesanmi,O. S. and Karagoz,I. D. and Kİlİc,I. H. and Ebuehi,O. A. T., 20133040728, English, Journal article, USA, 1940-6223, 5, (4), International Journal of Applied Research in Natural Products, (19–27), Healthy Synergies Publications, Cytotoxic and antiproliferative activity of Securidaca longepedunculata aqueous extract on Ehrlich ascites carcinoma cells in Swiss albino mice., (2012).
  • Luo, X., Pires, D., Aínsa, J. A., Gracia, B., Mulhovo, S., Anes, E., & Ferreira, M. J. U. (2011). Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique. Journal of Ethnopharmacology, 137(1), 114–120.
  • Mongalo, N. I., McGaw, L. J., Finnie, J. F., & Van Staden, J. (2015). Securidaca longepedunculata Fresen (Polygalaceae): A review of its ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology. Journal of Ethnopharmacology, 165, 215–226.
  • Ojewole, J. A. O. (2008). Analgesic, anti-inflammatory and hypoglycaemic effects of Securidaca longepedunculata (Fresen.) [Polygalaceae] root-bark aqueous extract. Inflammopharmacology, 16(4), 174–181.
  • Prance, G. T., & Jongkind, C. C. H. (2015). Polygalaceae. In Flora of West Tropical Africa. Royal Botanic Gardens, Kew.
  • Rakuambo, Meyer JJ, Rakuambo NC, Hussein AA. Novel xanthones from Securidaca longepedunculata with activity against erectile dysfunction. J Ethnopharmacol. 2008 Oct 28;119(3):599-603. doi: 10.1016/j.jep.2008.06.018. Epub 2008 Jun 27. PMID: 18638534.

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Compounds of Securidata longependuculat
References

Adebayo, M. A., Karioti, A., Skaltsa, H., & Ogunwande, I. A. (2007). Essential oils of Nigeria II: analysis of the leaf oil of Securidaca longependuculata Fers. Journal of Essential Oil Research, 19(5), 452-454.