Moringa oleifera

Moringa oleifera

Scientific Classification:

  • Kingdom: Plantae
  • Clade: Angiosperms
  • Order: Brassicales
  • Family: Moringaceae
  • Genus: Moringa
  • Species: M. oleifera

Synonyms:

Species ID: NMP-290,NCBI_Taxonomy ID: 3735,wfo-0001085051

Common Names: Moringa, drumstick tree, horseradish tree or malunggay

Local Names:

Zogale (Nigeria, Hausa), Ewe ile (Nigeria, Yoruba), Ben aile, Benzolive (French), Mlonge, Mronge, Mrongo, Mlongo, Mzunze, Mzungu (Kenya, Swahili), Cham’mwanba, Kangaluni (Malawi, Chichewa), Kalokola (Malawi, Yao), Nsangoa (Malawi, Senna), Yevu-ti (Ghana, Ewe), Argentiga, Arzam tigha ("The tree of paradise") (Burkina Faso, More), Guilgandani, Gigandjah (Burkina Faso, Fulfulde), and Zogala gandi (Niger, Hausa).

Basic Description:

Moringa oleifera is a deciduous tree that can reach a height of 10–12 meters with a trunk diameter of approximately 45 centimeters. It features a whitish-gray bark surrounded by thick cork. The tree has an open crown with drooping, fragile branches and feathery foliage composed of tripinnate leaves. The flowers are fragrant, hermaphroditic, and have five unequal, thinly veined, yellowish-white petals. The fruit is a hanging, three-sided brown capsule, 20–45 centimeters long, containing dark brown, globular seeds with three whitish, papery wings.

Distribution and Habitat:

Moringa oleifera is native to northern India but has been widely cultivated across tropical and subtropical regions worldwide, including Africa, South and Southeast Asia, the Caribbean, and South America. It thrives in a variety of soil types but prefers well-drained sandy or loamy soils with a slightly acidic to neutral pH. The tree is drought-resistant and flourishes in areas with annual rainfall ranging from 250 to 1500 millimeters.

Medicinal Properties:

Moringa oleifera is renowned for its extensive medicinal applications:

Nutritional Supplement

Moringa oleifera is an exceptional source of nutrients, making it a dietary supplement for combating malnutrition:

  • Vitamins: Rich in vitamins A (beta-carotene), B-complex (B1, B2, B3, and B6), C, D, E, and K.
  • Minerals: Contains calcium, magnesium, iron, zinc, potassium, and phosphorus.
  • Proteins: The leaves contain essential amino acids, making them a valuable protein source.

 Antimicrobial Properties

M. oleifera contains compounds with antimicrobial effects:

  • Antibacterial Activity: Effective against pathogens like Staphylococcus aureus, Escherichia coli, Salmonella typhi, and Pseudomonas aeruginosa.
  • Antifungal Activity: Active against fungi such as Candida albicans.
  • Antiviral Activity: Extracts have demonstrated antiviral properties, particularly against herpes simplex virus and certain enteroviruses.

Antioxidant Properties

The plant is rich in antioxidants, including:

  • Flavonoids: Quercetin and kaempferol neutralize free radicals, reducing oxidative stress.
  • Phenolic Acids: Gallic acid and chlorogenic acid protect against oxidative damage.
  • Vitamin C and E: Enhance cellular protection from free radical damage.

Anti-inflammatory Effects

M. oleifera exhibits significant anti-inflammatory activity due to the presence of:

  • Isothiocyanates: Compounds like niazimicin reduce inflammation at the cellular level.
  • Flavonoids and Polyphenols: Suppress inflammatory mediators, offering relief in arthritis, asthma, and autoimmune conditions.

Antidiabetic Properties

  • Hypoglycemic Activity: Compounds in the leaves and seeds, such as chlorogenic acid and isothiocyanates, lower blood sugar levels by improving insulin sensitivity and reducing glucose absorption in the gut.
  • Reduction of Postprandial Glucose: Studies show a significant decrease in blood sugar levels after meals when M. oleifera is consumed.

Cardioprotective Effects

M. oleifera helps maintain cardiovascular health through:

  • Cholesterol Reduction: Contains β-sitosterol, which reduces LDL cholesterol and triglycerides.
  • Blood Pressure Regulation: Isothiocyanates and nitrile glycosides relax blood vessels and reduce hypertension.

Hepatoprotective Effects

  • Liver Detoxification: Protects the liver from toxin-induced damage through antioxidant and anti-inflammatory actions.
  • Liver Enzyme Regulation: Normalizes elevated liver enzymes, supporting liver function in conditions like hepatitis.

Anticancer Properties

M. oleifera demonstrates anticancer potential due to the following compounds:

  • Isothiocyanates: Induce apoptosis (programmed cell death) in cancer cells.
  • Quercetin and Chlorogenic Acid: Prevent cancer cell proliferation and metastasis.
  • Niazimicin: Suppresses tumor formation.

These compounds have shown efficacy in breast, colon, lung, and skin cancers.

Gastroprotective Effects

Moringa oleifera is used to treat digestive disorders such as ulcers, gastritis, and diarrhea:

  • Anti-ulcer Activity: Leaf extracts protect the gastric lining and promote mucosal healing.
  • Antimicrobial Action: Fights against gut pathogens causing diarrhea.

Immune Modulation

  • Immune Boosting: High levels of vitamin C and bioactive compounds enhance the immune response.
  • Anti-allergenic Properties: Helps in managing allergic conditions by suppressing histamine release.

Wound Healing

  • Topical Applications: The leaves and seed oil are applied to cuts and wounds to promote faster healing and prevent infections.
  • Collagen Production: Enhances tissue repair and reduces scarring.

Water Purification and Antitoxic Effects

  • Coagulant Activity: Powdered seeds act as a natural coagulant, purifying water by removing turbidity and bacteria.
  • Chelating Properties: Helps detoxify heavy metals from the body.

Key Bioactive Compounds

The medicinal properties of Moringa oleifera are attributed to its diverse phytochemicals:

  • Alkaloids: Moringinine for vascular health.
  • Isothiocyanates: Anti-inflammatory and anticancer activity.
  • Flavonoids: Antioxidant and antidiabetic effects.
  • Tannins: Gastroprotective and antimicrobial action.
  • Saponins: Cardioprotective and immune-enhancing properties.

Known Toxicity:

While Moringa oleifera is generally considered safe for consumption, certain parts of the plant, particularly the roots and bark, contain alkaloids that may cause adverse effects if consumed in large quantities. Laboratory studies suggest that high doses of leaf extracts exceeding 3,000 mg/kg of body weight may be toxic, whereas doses below 1,000 mg/kg are considered safe. Additionally, M. oleifera may interact with prescription drugs metabolized by cytochrome P450 enzymes, potentially inhibiting their efficacy.

Additional Information:

Beyond its medicinal uses, Moringa oleifera serves various other purposes:

  • Agricultural Uses: The plant is used as a growth enhancer; extracts from the leaves can increase crop yields when applied as a foliar spray.
  • Water Purification: Powdered seeds act as a natural coagulant, aiding in water purification by causing suspended particles to clump together and settle.
  • Oil Production: The seeds yield ben oil, a non-drying oil used in cooking and cosmetics due to its stability and resistance to rancidity.

References:

  1. Moringa oleifera. (n.d.). In Wikipedia. Retrieved January 19, 2025, from https://en.wikipedia.org/wiki/Moringa_oleifera
  2. Moringa / Moringa oleifera. (n.d.). In Infonet Biovision Home. Retrieved January 19, 2025, from https://infonet-biovision.org/trees/moringa-moringa-oleifera
  3. Moringa Genus: A Review of Phytochemistry and Pharmacology. (2018). In Frontiers in Pharmacology. Retrieved January 19, 2025, from https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00108/full
  4. Esta planta deja atrás al jengibre y se convierte en el gran regulador del azúcar en sangre. (2024, October 10). In HuffPost España. Retrieved January 19, 2025, from https://www.huffingtonpost.es/life/salud/esta-planta-deja-jengibre-convierte-gran-regulador-azucar-sangre.html
  5. A Review on Meracle tree: Moringa oleifera - Pharmacognosy. (2016). In Journal of Pharmacognosy and Phytochemistry. Retrieved January 19, 2025, from https://www.phytojournal.com/archives/2016/vol5issue6/PartC/5-5-35-246.pdf

External links

  1. https://www.gbif.org/species/3580243
  2. https://ceb.wikipedia.org/wiki/Leptadenia_hastata
  3. https://www.gbif.org/species/194842538
  4. https://identify.plantnet.org/prota/species/Leptadenia%20hastata%20Vatke/data
  5. https://en.wikipedia.org/wiki/Moringa_oleifera
  6. https://www.feedipedia.org/node/124
  7. https://www.ajol.info/index.php/agrosh/article/view/93735

More Pictures


Compounds of Moringa oleifera
References

Aja, P. M., Nwachukwu, N., Ibiam, U. A., Igwenyi, I. O., Offor, C. E., & Orji, U. O. (2014). Chemical constituents of Moringa oleifera leaves and seeds from Abakaliki, Nigeria. American Journal of Phytomedicine and Clinical Therapeutics, 2(3), 310-321.