Synedrella nodiflora

Synedrella nodiflora

Synedrella nodiflora

Common Names: Synedrella, Cinderella weed, nodeweed, pig grass
Local Names: Akara ajẹ, alugannbi, aworo ona, ewe popo (Yoruba, Nigeria), Tanaposo (Nigeria), Okuaninvbo (Edo, Nigeria).
Species ID: NMP-172 |
wfo-0000075384 | NCBI_Taxonomy ID: 183085

Scientific Classification

Kingdom: Plantae

Clade: Tracheophytes

Clade: Angiosperms

Order: Asterales

Family: Asteraceae

Genus: Synedrella

Species: S. nodiflora

Binomial Name: Synedrella nodiflora (L.) Gaertn.

Synonyms: Blainvillea latifolia var. latifoliaUcacou nodiflorum (L.) Hitchc., Verbesina nodiflora L., Wedelia cryptocephala Peter

Morphological Description

Synedrella nodiflora, commonly referred to as Cinderella weed or nodeweed, is an annual or short-lived perennial herb that typically grows to heights of 30–100 cm, occasionally reaching 150 cm in fertile soils (Kew Science, 2024). The stems are erect to procumbent, dichotomously branched, and covered with short, rough hairs, giving a slightly prickly texture. Leaves are simple, opposite, elliptic to ovate, 3–12 cm long and 1–5 cm wide, with finely toothed margins, a glossy upper surface, and a pubescent underside (Tropical Plants Database, 2024). The plant produces small, yellow flower heads, 5–10 mm in diameter, arranged in axillary and terminal clusters, each containing 10–20 tubular florets with 3–5 ray florets, blooming year-round in tropical climates (Adams, 1972). Fruits are achenes, 3–4 mm long, flattened, with a bristly pappus aiding wind dispersal (CABI, 2024).

Distribution and Habitat

Native to tropical and subtropical Americas, from southern Mexico through Central America to northern South America and the Caribbean, Synedrella nodiflora has become widely naturalized in West Africa (e.g., Nigeria, Ghana), Southeast Asia (e.g., Malaysia, Philippines), northern Australia, and Pacific islands like Hawaii (Kew Science, 2024; CABI, 2024). It thrives in disturbed areas such as farmlands, roadsides, waste grounds, and pastures, often becoming a weed in banana, yam, and maize plantations (Tropical Plants Database, 2024). The species prefers seasonally dry tropical biomes, adapting to a range of soils—sandy, loamy, or clay—with a pH of 5.0–7.5, and grows optimally in warm, humid conditions with annual rainfall of 800–2,000 mm and temperatures of 20–32°C, at elevations up to 1,500 meters (Hutchinson & Dalziel, 1958).

Ethnopharmacology

Synedrella nodiflora is a significant plant in traditional medicine across its native and naturalized ranges, attributed to its bioactive compounds, including flavonoids, alkaloids, tannins, and terpenoids (Chaniad et al., 2021). Below are key ethnopharmacological uses supported by research:

·       Antimalarial Activity: In Nigeria, whole-plant decoctions treat malaria; ethanolic extracts (200–400 mg/kg) suppressed Plasmodium berghei parasitemia by 65–80% in mice, comparable to chloroquine, due to flavonoids and phenolic acids (Chaniad et al., 2021).

·       Anti-inflammatory and Analgesic: In Ghana, leaf poultices relieve fever and pain; methanol extracts reduced carrageenan-induced paw edema in rats by 50% at 300 mg/kg, linked to anti-inflammatory terpenoids (Agyare et al., 2013).

·       Antimicrobial Properties: In the Philippines, juice from crushed leaves treats infections and wounds; The ethanol extract demonstrated significant antibacterial activity against multiple bacterial strains (Wijaya et al., 2011).

·       General Tonic: In Benin, infusions are used as a health tonic.

These applications highlight its phytochemical diversity, with over 30 compounds identified, enhancing its therapeutic potential (Chaniad et al., 2021).

⚠  Toxicity Profile: Acute toxicity studies indicate Synedrella nodiflora is safe at traditional doses, with no mortality in rats at 2,000 mg/kg of ethanolic extract, though mild sedation was observed at higher doses (Chaniad et al., 2021).

Additional Uses

·       Fodder and Nutrition: Leaves, with 2–4% protein and 10–20 mg/100 g vitamin C, are used as fodder for goats and cattle in Nigeria and as a minor vegetable in soups (Adelakun et al., 2014).

·       Ornamental Value: Its yellow flowers and adaptability make it a minor ornamental in tropical gardens, attracting pollinators like bees (Tropical Plants Database, 2024).

·       Ecological Role: It acts as a pioneer species in disturbed areas, stabilizing soil and supporting biodiversity, though its weed status can challenge crops (CABI, 2024).

References

  • Adams, C. D. (1972). Flowering plants of Jamaica. University of the West Indies Press.
  • Adelakun, K. M., Mustapha, M. K., Ogundiwin, D. I., & Ihidero, A. A. (2014). Nutritional and anti-nutrient composition of Karaya gum tree (Sterculia setigera) seed: A potential fish feed ingredient. Journal of Agricultural Science and Technology, 1, 48–57.
  • Agyare, C., Asase, A., Lechtenberg, M., Niehues, M., Deters, A., & Hensel, A. (2013). An ethnopharmacological survey and in vitro confirmation of ethnopharmacological use of medicinal plants used by the people of the Ashanti Region, Ghana. Journal of Ethnopharmacology, 150(2), 389–398. doi: 10.1016/j.jep.2014.10.029.
  • CABI. (2024). Synedrella nodiflora (nodeweed). CABI Digital Library. Retrieved April 9, 2025, from https://www.cabidigitallibrary.org/doi/10.1079/cabicompendium.52325
  • Chaniad, P., Techarang, T., Phuwajaroanpong, A., Na-Ek, P., Viriyavejakul, P., & Punsawad, C. (2021). In vivo antimalarial activity and toxicity study of extracts of Tagetes erecta L. and Synedrella nodiflora (L.) Gaertn. from the Asteraceae family. Evidence-Based Complementary and Alternative Medicine, 2021, doi: 10.1155/2021/1270902.
  • Hutchinson, J., & Dalziel, J. M. (1958). Flora of West Tropical Africa (Vol. 2). Crown Agents for Oversea Governments and Administrations.
  • Wijaya, S., Nee, T. K., Jin, K. T., Hon, L. K., San, L. H., & Wiart, C. (2011). Antibacterial and antioxidant activities of Synedrella nodiflora (L.) Gaertn.(Asteraceae). Journal of complementary and Integrative Medicine, 8(1), 1-13.
  • Saka, K. L., Kudirat, O., James, O. O., & Olugbenga, F. T. (2013). The effects of the leaf water extract of Struchium sparganophora (Linn.) Ktze asteraceae on the hematopoietic parameters and the organ system of rats. Pakistan Journal of Pharmaceutical Sciences, 26(6), 1203-1207.
  • Tropical Plants Database. Synedrella nodiflora. Retrieved from https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:252024-1

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Compounds of Synedrella nodiflora
References

Adesanwo, J. K., Egbomeade, C. O., Moronkola, D. O., & Akinpelu, D. A. (2019). Chemical, toxicity and antibacterial studies on methanol extracts of Melanthera scandens, Ageratum conyzoides, Aspilia Africana and Synedrella nodiflora. Journal of Exploratory Research in Pharmacology, 4(1), 1-7.