Newbouldia laevis

Newbouldia laevis

Newbouldia laevis

Common Names: Tree of Life, Fertility Tree, African Border Tree
Local Names: Ewe Akoko (Yoruba, Nigeria), Ogilisi, Ogirishi (Igbo, Nigeria), Aduruku (Hausa, Nigeria), Ikhimi (Edo, Nigeria), Faangum (Cameroon)
Species ID: NMP-119 |
wfo-0000779153 | NCBI_Taxonomy ID: 211924

Scientific Classification

Kingdom: Plantae

Clade: Tracheophytes

Clade: Angiosperms

Clade: Eudicots

Clade: Asterids

Order: Lamiales

Family: Bignoniaceae

Genus: Newbouldia

Species: N. laevis

Authority: (P.Beauv.) Seem. ex Bureau

Synonyms: Spathodea speciosa C.Morren, Spathodea laevis P.Beauv., Newbouldia pentandra (Hook.) Seem.

Morphological Description

Newbouldia laevis is an evergreen shrub or small tree in the Bignoniaceae family, typically 3–8 m tall in western Africa, but reaching 15–20 m in the east:

·       Trunk: Straight, 30–90 cm in diameter, with smooth to slightly fissured greyish-brown bark (Burkill, 1985).

·       Leaves: Compound, pinnate, 20–40 cm long, with 5–9 glossy, dark green leaflets, 7–15 cm long (Fern, 2024).

·       Flowers: Bright pink to purple, tubular, 3–5 cm long, borne in terminal panicles, attracting pollinators like bees (Barwick, 2004).

·       Fruit: Woody capsules, 15–25 cm long, brown when mature, splitting to release flat, winged seeds (Burkill, 1985).

Distribution and Habitat

Newbouldia laevis is native to tropical Africa, widely distributed across West and Central regions:

·       Range: Senegal to Angola, east to Uganda and Cameroon; cultivated in Nigeria, Ghana, Togo (Fern, 2024).

·       Habitat: Savannas, woodlands, secondary forests, forest edges; thrives in 25–35°C, rainfall 1,000–2,500 mm/year, well-drained soils, 0–1,200 m elevation (Burkill, 1985).

Ethnopharmacology

Newbouldia laevis (African Border Tree) is widely used in traditional medicine for its antimicrobial properties, effectively combating Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus sp., Staphylococcus epidermidis, and Candida albicans, making it beneficial for treating wound infections and bacterial diseases. It also exhibits antitumor and anticancer potential due to its flavonoid and tannin content, while its antioxidant properties protect cells from oxidative stress. The plant has anti-inflammatory and analgesic effects, aiding in arthritis, rheumatism, and general pain relief, and is traditionally used for malaria and parasitic infections. It promotes wound healing, skin treatment, and digestive health, helping with stomach ulcers, diarrhea, and gastrointestinal infections. Additionally, it is known for its aphrodisiac and fertility-enhancing effects, as well as its potential to regulate blood pressure and support heart health. Its use extends to respiratory ailments like coughs, colds, and bronchitis, making it a versatile medicinal plant with significant therapeutic potential.

·       Pain Relief: Leaf paste in Senegal treats arthritis. Usman et al. (2014) found flower extract (200 mg/kg) reduced acetic acid-induced writhing in rats by 60%.

·       Headache: Heated leaves in Gabon applied to the head. Burkill (1985) notes its analgesic use in folk medicine.

·       Earache: Inner bark in Nigeria for ear infections. Burkill (1985) documents its topical application.

·       Eye Conditions: Leaf decoctions in Ghana treat conjunctivitis. Burkill (1985) confirms its ophthalmic use.

·       Digestive Issues: Root decoctions in Ivory Coast for dysentery. Okagu et al. (2024) report antimicrobial activity against Escherichia coli.

·       Diabetes: Leaves in Benin for glucose control. Mbagwu et al. (2020) showed butanol fraction (604 mg/kg) reduced blood glucose in diabetic mice by 45%.

·       Milk Production: Leaves in Nigeria ease delivery. Bafor et al. (2010) found leaf extract increased uterine contractions in rats by 30%.

·       Antimicrobial: Bark in Cameroon fights infections. The study on Newbouldia laevis leaves demonstrated significant antimicrobial activity, with the ethanolic extract exhibiting the highest inhibition against Proteus sp., Klebsiella pneumoniae, and Escherichia coli (14.5mm), followed by Staphylococcus aureus (13.85mm) and Pseudomonas aeruginosa (13.86mm). Chukwuma et al. (2016).

⚠  Toxicity Profile: Prolonged use of leaf extract (>600 mg/kg for 180 days) caused liver and kidney damage in rats, with elevated creatinine and AST levels. Avoid high doses in pregnancy due to uterotonic effects (Kolawole et al., 2021; Bafor et al., 2010).

Additional Uses

·       Cultural: Planted as boundary markers and used in chieftaincy ceremonies in Nigeria; leaves in Yoruba caps (Fern, 2024).

·       Timber: Soft wood (density 0.4 g/cm³) for carvings, utensils, fuelwood (Barwick, 2004).

·       Ecological: Fast-growing, used for erosion control and shade in agroforestry (Burkill, 1985).

References

  • Bafor, E. E., Omokaro, E. O., & Uwumarongie, O. H. (2010). Uterine contractile effects of the aqueous and ethanol leaf extracts of Newbouldia laevis (Bignoniaceae) in vitro. Pharmaceutical Biology48(9), 1029–1035. DOI: 10.4103/0250-474X.54274
  • Barwick, M. (2004). Tropical and subtropical trees: A worldwide encyclopaedic guide. Thames & Hudson.
  • Boucherle, B., Haudecoeur, R., Queiroz, E. F., De Waard, M., Wolfender, J. L., Robins, R. J., & Boumendjel, A. (2016). Nauclea latifolia: Biological activity and alkaloid phytochemistry of a West African tree. Natural Product Reports33(9), 1034–1043. https://doi.org/10.1039/C6NP00039H
  • Burkill, H. M. (1985). The useful plants of West Tropical Africa (Vol. 1). Royal Botanic Gardens, Kew.
  • Fern, K. (2024). Newbouldia laevis. Useful Tropical Plants Database. Retrieved from http://tropical.theferns.info/viewtropical.php?id=Newbouldia+laevis
  • Kolawole, O. T., Adeyeba, O. A., Awodele, O., Ayankunle, A. A., Wakeel, O. K., Oluogun, W., & Olaniyi, O. S. (2021). Evaluation of chronic toxicity of Newbouldia laevis leaf extract in rats. Tropical Journal of Natural Product Research5(10), 1889–1895.
  • Okagu, I. U., Ndefo, J. C., & Agbo, M. O. (2021). Trado-medical uses, chemical constituents and biological activities of Newbouldia laevis (Bignoniaceae): a review. Pharmaceutical Sciences, 28(1), 51-75. DOI: 10.1016/j.jep.2020.112555
  • Usman, M. R., Salawu, A. O., & Yahaya, T. (2014). Analgesic and anti-inflammatory screening of Newbouldia laevis flower in rodents. Journal of Medicinal Plants Research8(23), 847–852. https://scialert.net/abstract/?doi=tmr.2008.10.15

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Compounds of Newbouldia laevis
References


Osigwe, C. C., Akah, P. A., Nworu, C. S., & Okoye, F. B. (2017). Apigenin: A methanol fraction component of Newbouldia laevis leaf, as a potential antidiabetic agent. J. Phytopharm, 6, 38-44.