Cucumis melo

Cucumis melo

Cucumis melo

Common Names: Melon, Muskmelon, Cantaloupe, Honeydew
Local Names: India: Kharbooja (Hindi), Kachri (Punjabi) | Nigeria: Abaara-ekate (Yoruba) | Pakistan: Sarda (Urdu) | China: Tian Gua (Mandarin)
Species ID: NMP-029 |
wfo-0000628914| NCBI_Taxonomy ID: 3656

Scientific Classification

Kingdom: Plantae

Clade: Tracheophytes

Clade: Angiosperms

Clade: Eudicots

Clade: Rosids

Order: Cucurbitales

Family: Cucurbitaceae

Genus: Cucumis

Species: C. melo

Binomial Name: Cucumis melo L.

Synonyms: Cucumis acidus Jacq., Cucumis agrestis (Naudin) Greb., Cucumis callosus (Rottler) Cogn., Cucumis conomon Thunb., Cucumis dudaim L., Cucumis flexuosus L., Cucumis trigonus Roxb., Melo adana Pangalo

Morphological Description

Cucumis melo is an annual, trailing vine, often sprawling 1.5–3 m long, with hairy, ridged stems. Its features include:

·       Leaves: Large, orbicular to reniform, 5–20 cm in diameter, shallowly 5–7 lobed, rough-textured, hairy on both surfaces

·       Flowers: Yellow, 2–3 cm across, monoecious (staminate clustered, pistillate solitary), blooming June–September

·       Fruit: Pepo, highly variable—globose to oblong, 5–30 cm long, rind smooth (honeydew), netted (muskmelon), ribbed (cantaloupe), or wrinkled (casaba); flesh white, green, orange, or pink, sweet or bland, musky or inodorous

·       Seeds: Numerous, elliptic, compressed, 4–13 mm long, creamy white

The fruit’s diversity reflects centuries of cultivation (Pitrat, 2017).

Distribution and Habitat

Cucumis melo likely originated in the Middle East (Iran to India) or Africa, with wild forms in Sudan and Kenya. Cultivated for over 4,000 years, it’s now grown globally in:

·       Regions: Tropics and subtropics, including Asia, Africa, Europe, and the Americas

·       Climate: Warm, 25–35°C, with rainfall of 500–1,500 mm annually

·       Soil: Well-drained, sandy loam (pH 6.0–7.0)

·       Elevation: Sea level to 1,500 m

It thrives in sunny, arid conditions, often along ancient trade routes (Renner & Pandey, 2013).

Ethnopharmacology

Cucumis melo is valued in traditional medicine across cultures, supported by studies:

·       Hydration/Diuretic: High water content (90%) used in India for cooling and kidney stones; seed extracts increase urine output in rats (400 mg/kg) (Ravishankar & Priya, 2012).

·       Anti-inflammatory: Fruit pulp in Pakistan reduces fever; methanol extract lowers paw edema in rats (40% at 300 mg/kg) (Parmar & Kar, 2008).

·       Antioxidant: Seeds in Nigeria treat oxidative stress; peel extracts show DPPH IC₅₀ of 20 µg/mL (Boualam et al., 2021).

·       Digestive Aid: Fiber-rich fruit in Ayurveda relieves constipation; pulp used in Mali for stomach aches (Burkill, 1985).

·       Analgesic: Root decoctions in Sudan ease pain; seed extracts reduce writhing in mice (50% at 150 mg/kg) (Asif et al., 2022).

·       Anticancer: Seed oil in Egypt for tumors; extracts inhibit colon cancer cells (IC₅₀ 15 µg/mL) (Ibrahim et al., 2023).

Phytochemistry

Bioactivity arises from diverse compounds:

·       Flavonoids: Quercetin, kaempferol—antioxidant, anti-inflammatory (Boualam et al., 2021)

·       Carotenoids: β-carotene, lutein—vision health, oxidative protection (Asif et al., 2022)

·       Vitamins: C (ascorbic acid), A—immune support (Pitrat, 2017)

·       Fatty Acids: Linoleic acid in seeds—cardioprotective (Silva et al., 2020)

·       Terpenoids: Anticancer potential (Ibrahim et al., 2023)

⚠  Toxicity Profile: Generally safe; seeds contain minor cucurbitacins, potentially causing nausea at high doses. No acute toxicity reported at traditional levels (LD₅₀ > 2,000 mg/kg in rats). Caution advised in pregnancy due to limited data (Parmar & Kar, 2008).

Additional Uses

·       Culinary: Eaten fresh, juiced, or in desserts; seeds roasted or pressed for oil

·       Economic: Peel waste for biofuels; seeds for cosmetics (Silva et al., 2020)

·       Cultural: Used in Indian festivals for offerings

·       Agricultural: Susceptible to pests (aphids, powdery mildew); stored refrigerated post-ripening

References

  • Asif, H. M., Akhtar, N., Sultana, S., & Rehman, S. U. (2022). Medicinal properties of Cucumis melo Linn. Journal of Pharmacy and Pharmaceutical Sciences, 2, 58–62.
  • Boualam, K., Ndiaye, B., Harhar, H., Tabyaoui, M., Ayessou, N., & Taghzouti, K. (2021). Study of the phytochemical composition, antioxidant and anti-inflammatory effects of Piliostigma and Cucumis meloAdvances in Pharmacological and Pharmaceutical Sciences, 2021, 5549478. https://doi.org/10.1155/2021/5549478
  • Burkill, H. M. (1985). The Useful Plants of West Tropical Africa (2nd ed., Vol. 1, pp. 308–310). Royal Botanic Gardens, Kew.
  • Ibrahim, S. R. M., Mohamed, G. A., & Elkhayat, E. S. (2023). A scoping review on Cucumis melo and its anti-cancer properties. Anti-Cancer Agents in Medicinal Chemistry, 23(5), 512–525.
  • Parmar, H. S., & Kar, A. (2008). Protective role of Cucumis melo fruit extract in testosterone-induced benign prostatic hyperplasia in rats. Phytotherapy Research, 22(10), 1356–1363.
  • Pitrat, M. (2017). Melon genetic resources: Phenotypic diversity and horticultural taxonomy. In J. Janick (Ed.), Plant Breeding Reviews (Vol. 41, pp. 167–200). Wiley.
  • Ravishankar, K., & Priya, P. S. V. (2012). Evaluation of diuretic effect of ethanolic seed extracts of Cucumis melo in rats. Journal of Pharmaceutical Sciences and Research, 4(8), 1890–1893.
  • Renner, S. S., & Pandey, A. K. (2013). The Cucurbitaceae of India: Accepted names, synonyms, geographic distribution, and additional notes. Phytotaxa, 135(1), 1–45.
  • Silva, M. A., Albuquerque, T. G., & Oliveira, M. B. P. P. (2020). Chemical composition and bioactive compounds of Cucumis melo L. seeds: Potential source for new trends of plant oils. Food Chemistry, 313, 126092.

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Compounds of Cucumis melo
References

Olajuyigbe, A. A., Amah, G. H., Adebawo, O. O., & Olajuyigbe, O. O. (2019). Extraction and GC-MS analysis of the fatty acids in commonly consumed melon seed varieties in Nigeria. GSC Biological and Pharmaceutical Sciences, 7(3), 077-092.