Senna occidentalis

Senna occidentalis

Senna occidentalis

Common Names: Coffee Senna, African Coffee, Styptic Weed, Septicweed, Stinking Weed
Local Names: Rai dore. Sanga sanga (Hausa, Nigeria), Akidi agbara (Igbo, Nigeria), Abo rere,
Oduduemerema (Yoruba, Nigeria).
Species ID: NMP-157 |
wfo-1200001901 | NCBI_Taxonomy ID: 126820

Scientific Classification

Kingdom: Plantae

Phylum: Tracheophyta

Class: Magnoliopsida

Order: Fabales

Family: Fabaceae

Genus: Senna

Species: S. occidentalis

Synonyms: Cassia occidentalis L., Cassia foetida Kunth, Ditremexa occidentalis (L.) Britton & Rose

Morphological Description

Senna occidentalis is a pantropical, erect, herbaceous shrub or small tree, typically growing 0.5–2 m tall, with a strong fetid odor. Its key features include:

·       Stem: Slender, softly hairy, branching extensively, green to reddish-brown

·       Leaves: Pinnate, 15–20 cm long, with 3–7 pairs of broadly elliptic to ovate leaflets, 3–7 cm long, 2–4 cm wide, acute at the apex

·       Flowers: Yellow, 1.5–2 cm wide, borne in short axillary racemes of 2–4 flowers, with six fertile stamens

·       Fruit: Flat, sickle-shaped pods, 8–12 cm long, 0.8–1 cm wide, green turning dark brown, containing 20–30 seeds

The plant’s foetid smell and coffee-like seeds distinguish it in its habitat (Fern, 2024).

Distribution and Habitat

Senna occidentalis is native to the Americas, from the southern United States to northern Argentina, but has naturalized across tropical and subtropical regions globally, including Africa, Asia, and Australia. It thrives in:

·       Ecosystems: Disturbed areas, wastelands, roadsides, pastures, and agricultural fields

·       Climate: Warm, humid tropics (20–35°C), rainfall 500–2,000 mm annually

·       Soils: Sandy to loamy, well-drained, tolerating poor fertility and drought

It is an aggressive weed, often outcompeting native vegetation (Shackleton et al., 2018).

Ethnopharmacology

Senna occidentalis, commonly known as coffee senna, is a plant with a rich history in traditional medicine, attributed to its diverse therapeutic properties. It has been traditionally used to treat liver disorders, diabetes, rheumatism, and skin diseases such as eczema and ringworm. The plant exhibits antibacterial and antifungal activities, making it effective against various pathogens. Additionally, S. occidentalis has been employed as a laxative to alleviate constipation and as a diuretic for promoting urine production. Its hepatoprotective effects suggest potential in safeguarding the liver from damage. Furthermore, the plant has been utilized in managing fevers, convulsions, and respiratory conditions like asthma. These medicinal properties are attributed to its rich phytochemical composition, including anthraquinones, flavonoids, tannins, and saponins. While these traditional uses are supported by various studies, further clinical research is necessary to fully establish the efficacy and safety of Senna occidentalis in these medicinal applications.​

·       Skin Diseases: In Nigeria, leaf pastes treat fungal infections; he leaves have been applied externally to manage conditions like itches, yaws, scabies, and ringworm. These therapeutic applications are supported by the plant's antifungal and antibacterial properties, which are attributed to bioactive compounds such as anthraquinones and flavonoids. rootextract of S. occidentalis has the potential to control growth of M. phaseolina (Javaid, 2022).

·       Fevers: In Ghana, leaf infusions reduced fever in rats by 1.5°C at 200 mg/kg, linked to anti-inflammatory flavonoids (Ojewole et al., 2003).

·       Gastrointestinal Issues: In Brazil, seed decoctions act as laxatives; anthraquinones (e.g., emodin) increased intestinal motility

·       Antimicrobial: methanol and aqueous extracts showedsignificant antimicrobial activity against most of the tested microbes. The most susceptible microorganism was P. aeruginosa (18mm zone of inhibition in aqueous extract) followed by P. mirabilis (15 mm zone of inhibition in methanol extract) and Candidaalbicans (8 mm zone of inhibition in methanol extract) (Arya, et al., 2010).

·       Hepatoprotective: a study demonstrated that an aqueous-ethanolic extract of the leaves significantly reduced liver enzyme levels elevated due to paracetamol and ethanol intoxication in rats, suggesting a protective effect on liver cells (Jafri et al., 1999).

⚠  Toxicity Profile: Seeds and leaves contain toxic anthraquinones (e.g., emodin) and N-methylmorpholine, linked to hepatomyoencephalopathy in children and livestock. Ingestion of seeds (>0.5 g/kg) causes muscle necrosis, respiratory failure, and death; LD₅₀ in rats is ~1,000 mg/kg (Silva et al., 2011).

Additional Uses

·       Coffee Substitute: Roasted seeds yield a coffee-like beverage in Sudan (Fern, 2024).

·       Fodder: Young leaves occasionally grazed by livestock, though toxic in quantity (Shackleton et al., 2018).

·       Cultural: In Hausa tradition, used in rituals for protection against evil spirits (Burkill, 1995).

References

  • Arya, V., Yadav, S., Kumar, S., & Yadav, J. P. (2010). Antimicrobial activity of Cassia occidentalis L (leaf) against various human pathogenic microbes. Life Sci Med Res, 9(1), e12.
  • Burkill, H. M. (1995). The useful plants of West Tropical Africa (2nd ed., Vol. 3). Royal Botanic Gardens, Kew.
  • Jafri, M. A., Subhani, M. J., Javed, K., & Singh, S. (1999). Hepatoprotective activity of leaves of Cassia occidentalis against paracetamol and ethyl alcohol intoxication in rats. Journal of Ethnopharmacology, 66(3), 355-361.
  • Javaid, A., Qudsia, H., Khan, I. H., Anwar, A., & Ferdosi, M. F. (2022). Antifungal activity of Senna occidentalis root extract against Macrophomina phaseolina and its GC-MS analysis. Pakistan Journal of Weed Science Research, 28(1), 115-122.
  • Ojewole, J. A. O. (2003). Evaluation of the anti-inflammatory properties of Senna occidentalis stem-bark extracts in rats. Journal of Ethnopharmacology85(2–3), 217–220. https://doi.org/10.1016/S0378-8741(03)00019-9
  • Shackleton, C. M., Hurley, J., & O’Connor, T. G. (2018). Invasive species in African savannas. Journal of Arid Environments155, 1–12.
  • Silva, M. G., Aragão, T. P., Vasconcelos, C. F., Ferreira, P. A., & Andrade, B. A. (2011). Acute and subacute toxicity of Senna occidentalis seeds in rats. Journal of Ethnopharmacology136(1), 177–183. DOI: 10.1016/j.jep.2011.04.070

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Compounds of Senna occidentalis
References

Lawal, A. M., Abdullahi, R., Ibrahim, M. S., Kurfi, M. Y., Khalid, A., & Nuhu, M. (2019). Phytochemical analysis and thin layer chromatography profiling of crude extracts from Senna occidentalis (leaves). Journal of Biotechnology and Biomedical Science, 2(1), 12-21.