Momordica balsamina

Momordica balsamina

Scientific Classification:

  • Kingdom: Plantae
  • Clade: Angiosperms
  • Order: Cucurbitales
  • Family: Cucurbitaceae
  • Genus: Momordica
  • Species: M. balsamina

Synonyms:

Species ID: NMP-288,wfo-0000376910,NCBI_Taxonomy ID: 3672

Common Names:

African cucumber, balsam apple, and balsam pear. Other names for M. balsamina are balsamina or southern balsam pear

Local Names:

Garahuni or Garafuni (Hausa), cacana (Mozambique) and nkaka (South Africa)

Basic Description:

Momordica balsamina is a climbing herb that can extend up to 5 meters in length. It features thin, angular, and slightly hairy stems. The leaves are alternately arranged, heart-shaped, and deeply lobed with serrated edges. The plant produces pale yellow flowers and round, somewhat warty, bright orange fruits. When ripe, the fruits split open to reveal numerous seeds encased in a brilliant scarlet, sticky coating.

Distribution and Habitat:

Momordica balsamina is native to tropical regions of Africa and the southwestern Arabian Peninsula. It has been introduced and become invasive in parts of Asia, Australia, Central America, and North America, including some areas in Florida. The plant thrives in lowland and montane rainforests, as well as disturbed areas.

Medicinal Properties:

Traditionally, Momordica balsamina has been utilized for various medicinal purposes:

·       Antimicrobial Properties: The leaves, fruits, and seeds of M. balsamina exhibit strong antimicrobial activity:

·       Antibacterial Activity: Extracts have been shown to inhibit the growth of bacterial pathogens such as Escherichia coli, Salmonella typhi, Staphylococcus aureus, and Pseudomonas aeruginosa. This supports its traditional use in treating infections and wounds.

·       Antifungal Activity: The plant is effective against fungal species such as Candida albicans and Aspergillus. (Ajayi et al., 2018)

·  Anti-inflammatory and Analgesic Properties: Momordica balsamina is used to treat inflammatory conditions such as arthritis and muscle pain. The anti-inflammatory effect is linked to the presence of flavonoids and saponins, which inhibit the release of pro-inflammatory mediators.

·   Antiplasmodial and Antimalarial Effects: The plant exhibits antimalarial activity, particularly against Plasmodium falciparum. The leaves and fruit extracts have been used traditionally to treat fevers and malaria. This is attributed to the alkaloids and flavonoids in the plant, which inhibit the growth of malaria parasites.

·       Antidiabetic Properties: The plant is used traditionally to manage diabetes. Compounds in the leaves and fruit help regulate blood glucose levels by increasing insulin sensitivity and reducing glucose absorption in the gut.

·       Antioxidant Activity: Momordica balsamina is a rich source of antioxidants, including phenolic compounds, flavonoids, and tannins. These compounds neutralize free radicals, reducing oxidative stress and its associated diseases, such as cardiovascular and neurodegenerative disorders.

·       Wound Healing:The leaves and fruit pulp are applied topically to cuts and wounds to promote healing. The antiseptic properties prevent infection, while the saponins and tannins enhance tissue repair.

·       Antiviral Properties: Compounds called momordins, isolated from M. balsamina, exhibit antiviral activity against HIV and other viruses. These proteins inhibit viral replication by targeting viral RNA.

·       Gastroprotective Effects: The plant is used to treat stomach ulcers, diarrhea, and intestinal infections. Its gastroprotective effects are due to the presence of tannins, which reduce gut inflammation and promote mucosal healing.

·   Liver Protective Activity: Studies suggest hepatoprotective effects, where the plant extracts mitigate liver damage induced by toxins or alcohol. This is attributed to its antioxidant activity.

·       Anticancer Potential: Preliminary studies indicate that extracts of M. balsamina may have anticancer activity. Compounds such as phenolics and flavonoids inhibit the proliferation of cancer cells in vitro.

·       Fertility Regulation: In some African cultures, the plant is used to regulate fertility. The seeds and fruits have been reported to have contraceptive properties, though the exact mechanism remains under study.

Known Toxicity:

While the plant has medicinal benefits, some sources indicate that the outer rind and seeds of the fruit may be poisonous. However, certain communities, such as the Tsonga people in southern Africa, consume the leaves and fruit after proper preparation. Caution is advised, and traditional knowledge should be consulted to ensure safe usage.

Additional Information:

Beyond its medicinal applications, Momordica balsamina has practical uses:

  • Soap Substitute: The fruit and leaves can be used as a soap substitute due to their saponin content.
  • Metal Cleaner and Arrow Poison: The plant sap serves as a metal cleaner and has been processed into an arrow poison in certain cultures.

References:

  1. Kew Science. (n.d.). Momordica balsamina L. Plants of the World Online. Retrieved from https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:293397-1
  2. Medicinal Plant Names Services. (n.d.). Momordica balsamina. Retrieved from https://mpns.kew.org/mpns-portal/plantDetail?plantId=2372858
  3. Momordica balsamina. (n.d.). In Wikipedia. Retrieved from https://en.wikipedia.org/wiki/Momordica_balsamina
  4. Momordica balsamica. (n.d.). In PlantZAfrica. Retrieved from https://pza.sanbi.org/momordica-balsamica
  5. Balsam apple facts and health benefits. (n.d.). In Health Benefits Times. Retrieved from https://www.healthbenefitstimes.com/balsam-apple/
  6. Momordica balsamina: A medicinal and nutraceutical plant for health care management. (n.d.). In Academia.edu. Retrieved from https://www.academia.edu/11620173/Momordica_balsamina_A_medicinal_and_neutraceutical_plant_for_health_care_management_Comments_Biotechnological_potential_of_M_balsamina_revealed
  7. Khan, M., Diop, A., Gbodossou, E., Xiao, P., Coleman, M., De Barros, K., ... & Powell, M. D. (2023). Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina. Virology Journal, 20(1), 50.

External links

  1. https://en.wikipedia.org/wiki/Momordica_balsamina
  2. https://pmc.ncbi.nlm.nih.gov/articles/PMC8821832/
  3. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/momordica-balsamina
  4. https://www.cabidigitallibrary.org/doi/full/10.1079/cabicompendium.34677
  5. https://pza.sanbi.org/momordica-balsamica
  6. https://virologyj.biomedcentral.com/articles/10.1186/s12985-023-02010-5
  7. https://www.mdpi.com/1661-3821/3/4/40
  8. https://www.mdpi.com/1661-3821/3/4/40
  9. https://www.ajol.info/index.php/sjvs/article/view/41461

More Pictures


Compounds of Momordica balsamina
References

Kabir, N., Umar, I. A., Dama, H. A., James, D. B., & Inuwa, H. M. (2021). Isolation and structural elucidation of novel antidiabetic compounds from Leaves of Momordica balsamina Linn and Leptadenia hastata (Pers) Decne. Iranian Journal of Pharmaceutical Research: IJPR, 20(2), 390.