Betulinic acid
| Compound Structure: |
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| Synonyms: | betulinic acid;472-15-1;Betulic acid;Mairin;Lupatic Acid;als-357;CCRIS 6748;NSC 113090;3-Hydroxylup-20(29)-en-28-oic acid;EINECS 207-448-8;beta-betulinic acid;3beta-Hydroxy-20(29)-lupaene-28-oic acid;NSC 677578 | ||||||||||||||||||||||||||||||||||||||||||
| Compound ID: | NMPC-668 | ||||||||||||||||||||||||||||||||||||||||||
| PubChem ID: | |||||||||||||||||||||||||||||||||||||||||||
| Molecular Formula: | C30H48O3 | ||||||||||||||||||||||||||||||||||||||||||
| Canonical SMILES: | CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=O)O | ||||||||||||||||||||||||||||||||||||||||||
| InChIKey: | QGJZLNKBHJESQX-FZFNOLFKSA-N | ||||||||||||||||||||||||||||||||||||||||||
| About the compound: | Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. It has a role as an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-HIV agent, an antimalarial, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of a lupane. Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. GHS Hazard Statements Not Classified Reported as not meeting GHS hazard criteria by 29 of 30 companies (only ~ 3.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Betulinic acid is a pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. It has a role as an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-HIV agent, an antimalarial, an anti-inflammatory agent, an antineoplastic agent and a plant metabolite. It is a pentacyclic triterpenoid and a hydroxy monocarboxylic acid. It derives from a hydride of a lupane. Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. GHS Hazard Statements Not Classified Reported as not meeting GHS hazard criteria by 29 of 30 companies (only ~ 3.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website. |
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| Properties: |
Chemical and Physical Properties
Source: PubChem |
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| Source Species: |
Glossonema boveanum Nauclea latifolia Parinari curatellaefolia Syzygium guineense Uapaca guineensis Momordica balsamina Leptadenia hastata Maesobotrya barteri |