Millettia thonningii

Millettia thonningii

Millettia thonningii

Common Names: Milletia, Thonning’s Millettia, African Rosewood
Local Names: Ito (Yoruba, Nigeria), Tuburku (Hausa, Nigeria), Ajukwu Okeokpa (Igbo, Nigeria), Kpaye (Ewe, Ghana)
Species ID: NMP-106 |
wfo-0000200787

Scientific Classification

Kingdom: Plantae

Clade: Tracheophytes

Clade: Angiosperms

Clade: Eudicots

Clade: Rosids

Order: Fabales

Family: Fabaceae

Subfamily: Faboideae

Genus: Millettia

Species: M. thonningii

Synonyms: Derris thonningii (Schumach.) Baker, Pongamia thonningii Schumach., Lonchocarpus thonningii (Schumach.) DC.

Morphological Description

Millettia thonningii is a deciduous tree native to tropical Africa, typically growing 10–20 m tall, occasionally reaching 35 m. Its key features include:

·       Habit: Medium to large tree with a spreading crown and drooping branches.

·       Bark: Grey-brown, smooth when young, becoming fissured with age; exudes a red sap when cut.

·       Leaves: Compound, pinnate, 20–40 cm long, with 7–13 elliptic leaflets, each 5–10 cm long, dark green above, paler beneath (Keay, 1989).

·       Flowers: Purple to violet, pea-like, 1–2 cm long, in dense, pendulous racemes up to 30 cm long, fragrant.

·       Fruit: Flat, woody pods, 10–20 cm long, 2–3 cm wide, brown, containing 2–6 flat seeds (Burkill, 1995).

Its vibrant flowers and legume pods are hallmarks of the Fabaceae family (Allen & Allen, 1981).

Distribution and Habitat

Millettia thonningii is widespread across tropical Africa, particularly West and Central regions:

·       Countries: Nigeria, Ghana, Senegal, Cameroon, DR Congo, Uganda, Côte d'Ivoire.

It thrives in lowland rainforests, gallery forests, savanna woodlands, and along riverbanks at elevations up to 1,500 m, preferring well-drained, loamy soils (pH 5.5–7.0) and humid climates (Burkill, 1995).

Ethnopharmacology

Millettia thonningii is a medicinal plant from the Fabaceae family, widely used in traditional African medicine for its diverse therapeutic properties. It is known for its anti-inflammatory, antimicrobial, analgesic, antimalarial, antidiabetic, and hepatoprotective effects. The plant contains bioactive compounds such as flavonoids, alkaloids, tannins, and saponins, which contribute to its medicinal benefits. It is used to treat wounds, skin infections, gastrointestinal disorders, fever, and liver-related ailments. The bark, leaves, and roots are commonly prepared as decoctions, infusions, or poultices. Despite its benefits, caution is advised, especially regarding dosage and prolonged use, due to potential toxicity.

·       Antischistosomal: Seed extracts in Ghana treat schistosomiasis. Lyddiard et al. (2002) found isoflavonoids like alpinumisoflavone (LC₅₀ 10 μg/mL) killed *Schistosoma mansoni* cercariae, inhibiting mitochondrial electron transport.

·       Anthelmintic: Root decoctions in Nigeria expel intestinal worms. Perrett et al. (1995) confirmed molluscicidal activity (LC₅₀ 20 ppm) against *Biomphalaria glabrata*, snail vectors of schistosomiasis, due to robustic acid.

·       Purgative: Bark infusions in Senegal act as laxatives. Burkill (1995) notes its traditional use, supported by saponin content.

·       Blood Purification: Pulverized roots in Cameroon cleanse blood. Ethnographic use aligns with antioxidant properties of flavonoids (Jena et al., 2020).

·       Analgesic: Leaf poultices in Togo relieve pain. Traditional claims suggest anti-inflammatory potential, though specific studies are limited (Banzouzi et al., 2008).

Phytochemicals include isoflavonoids (alpinumisoflavone, robustic acid), rotenoids (rotenone), saponins, and alkaloids, driving its medicinal efficacy (Lyddiard et al., 2002; Jena et al., 2020).

⚠  Toxicity Profile: Seeds and roots contain rotenone, a lipophilic rotenoid (LD₅₀ 132 mg/kg in rats), highly toxic to fish (LC₅₀ 0.1 ppm) and insects but less so to mammals due to poor absorption. Acute human toxicity is rare (LD₅₀ 143 mg/kg in children), with vomiting limiting fatalities. Rotenone degrades in sunlight within 6–10 days. High doses may cause liver irritation in rats (Jena et al., 2020; Allen & Allen, 1981).

Additional Uses

·       Construction: Durable wood used for furniture, tool handles, and carpentry (Keay, 1989).

·       Fuel: Branches and logs serve as firewood in rural areas (Burkill, 1995).

·       Agroforestry: Nitrogen-fixing roots improve soil fertility in mixed cropping systems (Allen & Allen, 1981).

·       Piscicide: Seed powder poisons fish for easy capture, safe for human consumption after cooking (Banzouzi et al., 2008).

References

  • Allen, O. N., & Allen, E. K. (1981). The Leguminosae: A source book of characteristics, uses, and nodulation. University of Wisconsin Press.
  • Banzouzi, J. T., Prost, A., Rajemiarimiraho, M., & Ongoka, P. (2008). Traditional uses of the African Millettia species (Fabaceae). International Journal of Botany 4(4): 406-420
  • Burkill, H. M. (1995). The useful plants of West Tropical Africa (Vol. 3). Royal Botanic Gardens, Kew.
  • Jena, R., Rath, D., Rout, S. S., & Kar, D. M. (2020). A review on genus Millettia: Traditional uses, phytochemicals and pharmacological activities. Saudi Pharmaceutical Journal, 28(12), 1686-1703. DOI: 10.1016/j.jsps.2020.10.015
  • Keay, R. W. J. (1989). Trees of Nigeria. Clarendon Press.
  • Lyddiard, J. R., Whitfield, P. J., & Bartlett, A. (2002). Antischistosomal bioactivity of isoflavonoids from Millettia thonningii (Leguminosae). Journal of Parasitology88(1), 163–170. https://doi.org/10.1645/0022-3395(2002)088[0163:ABOIFM]2.0.CO;2
  • Perrett, S., Whitfield, P. J., Sanderson, L., & Bartlett, A. (1995). The plant molluscicide Millettia thonningii (Leguminosae) as a topical antischistosomal agent. Journal of Ethnopharmacology47(1), 49–54. DOI: 10.1016/0378-8741(95)01253-a

External Links

More Pictures

 

Compounds of Millettia thonningii
References

Olaoluwa, O., Ibeh, E., Taiwo, O., Adeyemi, M., & Flamini, G. (2022). Essential Oil Characterization and Biological Activities of Millettia thonningii (Schumach. & Thonn.) Baker Leaf, Stem and Root. Journal of Essential Oil Bearing Plants, 25(4), 888-898.