Schumanniophyton magnificum

Schumanniophyton magnificum

Schumanniophyton magnificum

Common Names: Magnificent Shrub, Ogunfe
Local Names: Ogunfe (Yoruba, Nigeria), Mgba mmiri (Igbo, Nigeria), Nkom (Baka, Cameroon)
Species ID: NMP-151 |
wfo-0000307163 | NCBI_Taxonomy ID: 114490

Scientific Classification

Kingdom: Plantae

Phylum: Tracheophyta

Class: Magnoliopsida

Order: Gentianales

Family: Rubiaceae

Genus: Schumanniophyton

Species: S. magnificum

Synonyms: Schumanniophyton magnificum var. magnificumSchumanniophyton magnificum var. klaineanum (Perre ex A.Chev.) N.Hallé

Morphological Description

Schumanniophyton magnificum is a small to medium-sized tree or shrub, typically 4–5 m tall, occasionally reaching 10 m. Its key features include:

·       Stem: Soft-wooded, grayish-brown bark, often used medicinally

·       Leaves: Glossy, dark green, opposite, ovate to elliptic, 15–30 cm long, 10–15 cm wide

·       Flowers: White to yellowish, fragrant, borne in dense terminal clusters subtended by broad bracts

·       Fruit: Small, ovoid, 1–2 cm long, green turning brown, containing 1–2 seeds

Distribution and Habitat

Schumanniophyton magnificum is native to tropical Central and West Africa, spanning Nigeria, Cameroon, Gabon, and northern Angola. It thrives in:

·       Ecosystems: Lowland rainforests, riverbanks, and swampy areas (0–500 m altitude)

·       Soils: Moist, organic-rich, acidic soils (pH 4.5–6.0)

·       Climate: High humidity (80–90%), annual rainfall 1,500–3,000 mm, temperatures 25–30°C

It often grows near water sources, enhancing its accessibility for traditional use (Burkill, 1997).

Ethnopharmacology

Schumanniophyton magnificum, has been traditionally employed for various medicinal purposes, including treating dysentery, snake bites, and as a post-circumcision lotion. Scientific studies have substantiated several of these uses, revealing that extracts from the plant exhibit antibacterial activity against pathogens such as Escherichia coli and Staphylococcus aureus, supporting its application in managing urogenital infections. The plant also demonstrates anti-inflammatory properties through phospholipase A₂ inhibition, which may explain its traditional use in snake bite treatments. Additionally, S. magnificum has shown antihyperglycemic and antioxidant effects, suggesting potential benefits in managing insulin resistance and protecting against organ damage. Furthermore, the leaves exhibit antimalarial activity without notable toxicity, aligning with traditional malaria treatments.

·       Antimalarial: In Cameroon, bark extracts showed in vitro activity against chloroquine-resistant Plasmodium falciparum (IC₅₀ 10–50 µg/mL), linked to chromone glycosides (Bickii et al., 2007).

·       Anti-snake Venom: In Nigeria, stem bark peptides inhibited cobra venom effects on chick biventer cervicis muscle, attributed to schumanniofoside (Houghton & Harvey, 1989).

·       Antibacterial: Leaf extracts exhibited activity against Staphylococcus aureus (MIC 64 µg/mL), supporting wound treatment in Gabon (Joshua et al., 2020).

·       Anti-inflammatory: Bark decoctions reduced inflammation in dysentery treatment; linked to noreugenin and rohitukine (Tane et al., 1990).

·       Aphrodisiac: In Cameroon, aqueous extracts doubled testosterone levels (2.15 ± 0.70 ng/mL) in rats, supporting Baka Pygmy use (Wikipedia, 2023).

⚠  Toxicity Profile: No acute toxicity is well-documented; LD₅₀ of ethanolic leaf extract in mice is >2,000 mg/kg, suggesting low toxicity. Caution is advised due to bioactive compounds (Joshua et al., 2020).

Additional Uses

·       Cultural: Used in Gabonese rituals for its psychoactive properties, likened to Tabernanthe iboga (Wikipedia contributors, 2023).

·       Ecological: Stabilizes riverbank soils, reducing erosion (Fern, 2024).

·       Pharmacological: Chromone glycosides (e.g., schumanniofiosides A and B) are studied for drug development (Tane et al., 1990).

References

  • Bickii, J., Tchouya, G. R. F., Tchouankeu, J. C., & Tsamo, E. (2007). Antimalarial activity in crude extracts of some Cameroonian medicinal plants. African Journal of Traditional, Complementary and Alternative Medicines4(1), 107–111. https://doi.org/10.4314/ajtcam.v4i1.31200
  • Burkill, H. M. (1997). The useful plants of West Tropical Africa (2nd ed., Vol. 5). Royal Botanic Gardens, Kew.
  • Houghton, P. J., & Harvey, A. L. (1989). Investigation of the anti-snake venom activity of Schumanniophyton magnificumPlanta Medica55(3), 273–275. https://doi.org/10.1055/s-2006-962002
  • Joshua, P. E., Anosike, C. J., Asomadu, R. O., Ekpo, D. E., Uhuo, E. N., & Nwodo, O. F. C. (2020). Bioassay-guided fractionation, phospholipase A2-inhibitory activity and structure elucidation of compounds from leaves of Schumanniophyton magnificumPharmaceutical Biology58(1), 1069–1076. https://doi.org/10.1080/13880209.2020.1839510
  • Tane, P., Ayafor, J. F., Sondengam, B. L., & Connolly, J. D. (1990). Chromone glycosides from Schumanniophyton magnificumPhytochemistry29(6), 2003–2006. DOI: 10.1016/0031-9422(90)80071-n
  • Wikipedia contributors. (2023). Schumanniophyton. In Wikipedia, The Free Encyclopedia. Retrieved from https://en.wikipedia.org/wiki/Schumanniophyton

External Links

More Pictures

 

Compounds of Schumanniophyton magnificum
References

Joshua, P. E., Anosike, C. J., Asomadu, R. O., Ekpo, D. E., Uhuo, E. N., & Nwodo, O. F. C. (2020). Bioassay-guided fractionation, phospholipase A2-inhibitory activity and structure elucidation of compounds from leaves of Schumanniophyton magnificum. Pharmaceutical biology, 58(1), 1078-1085.