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                                        Scientific
Classification: 
 - Kingdom:
     Plantae
 
 - Clade:
     Angiosperms
 
 - Order:
     Lamiales
 
 - Family:
     Lamiaceae
 
 - Genus:
     Hyptis
 
 - Species:
     H. suaveolens
 
 Synonyms:  Species ID: NMP-286;wfo-0000217093;NCBI_Taxonomy ID: 204129 Common Names:  Local Names: Basic Description:  Hyptis suaveolens
is an erect, aromatic annual or perennial herb, typically reaching heights of 1
to 2.5 meters. It has square-shaped, hairy stems and oppositely arranged, ovate
to elliptic leaves with serrated margins. The leaves emit a strong minty aroma
when crushed. The plant produces small, pink to purple flowers clustered in the
upper leaf axils.  Distribution and
Habitat:  Native to tropical regions of the
Americas, Hyptis suaveolens has become naturalized in tropical and
subtropical areas worldwide, including Nigeria. It thrives in disturbed areas
such as roadsides, open fields, and wastelands, often favoring well-drained
soils and full sunlight.  Medicinal Properties:  Hyptis suaveolens
is utilized in traditional medicine for various therapeutic purposes: Antimicrobial
Activity 
 - H.
     suaveolens exhibits significant
     antimicrobial effects against various bacteria and fungi, such as Escherichia
     coli, Staphylococcus aureus, Candida albicans, and Aspergillus
     species.
 
 - The
     plant’s essential oils disrupt microbial membranes, inhibiting growth and
     reproduction of pathogens.
 
 2. Antioxidant
Activity 
 - The
     flavonoids and phenolic acids in H. suaveolens neutralize free
     radicals, reducing oxidative damage to cells and tissues.
 
 - Antioxidant
     properties play a role in preventing chronic diseases like cardiovascular
     disorders and diabetes.
 
 3. Anti-inflammatory
and Analgesic Effects 
 - The
     plant has been traditionally used to treat inflammation and pain.
 
 - Ursolic
     acid and oleanolic acid in H. suaveolens inhibit pro-inflammatory
     mediators, reducing swelling and pain in conditions such as arthritis.
 
 4. Antimalarial
Activity 
 - The
     ethanolic leaf extract has shown antiplasmodial effects against Plasmodium
     berghei in animal models.
 
 - This
     supports its use in traditional medicine for malaria management.
 
 5. Antidiabetic
Properties 
 - The
     plant aids in glucose regulation and insulin sensitivity.
 
 - Phytochemicals
     like flavonoids may enhance pancreatic β-cell function and lower blood
     sugar levels.
 
 6. Anticancer
Potential 
 - Preliminary
     studies suggest H. suaveolens may have cytotoxic effects on cancer
     cells.
 
 - Bioactive
     compounds such as flavonoids and phenolic acids have been linked to
     apoptosis in cancer cell lines.
 
 7. Respiratory Health 
 - Traditionally,
     the plant is used to treat respiratory issues like asthma, cough, and
     bronchitis.
 
 - The
     essential oils provide bronchodilation and antimicrobial effects,
     alleviating symptoms of respiratory tract infections.
 
 8. Gastrointestinal
Health 
 - The
     plant is effective against diarrhea, intestinal worms, and dyspepsia.
 
 - Its
     antimicrobial activity helps restore gut flora balance, while alkaloids
     provide relief from cramps and abdominal discomfort.
 
 9. Insecticidal and
Mosquito Repellent Activity 
 - Essential
     oils from H. suaveolens act as natural insecticides and are used to
     repel mosquitoes.
 
 - This
     property is attributed to its high camphor and eugenol content.
 
 Traditional Uses 
 - Wound
     Healing: Applied topically to wounds,
     burns, and skin infections for its antimicrobial and anti-inflammatory
     properties.
 
 - Fever
     and Colds: Decoctions of the leaves are
     consumed to reduce fever and treat flu-like symptoms.
 
 - Headaches
     and Migraines: Aromatherapy with its essential
     oils is used to alleviate headaches.
 
 - Menstrual
     Disorders: Used to regulate menstrual
     cycles and relieve cramps.
 
 Known Toxicity:  While Hyptis suaveolens is
widely used in traditional medicine, caution is advised due to potential
toxicity. Some studies have reported adverse effects at high doses, emphasizing
the need for proper dosage and consultation with healthcare professionals
before use. Additional
Information:  Beyond its medicinal applications, Hyptis
suaveolens is known for its insecticidal properties. The plant's essential
oil has been found to be as effective as DEET in repelling mosquitoes,
highlighting its potential as a natural alternative for vector control.  References: 
 - Kew
     Science. (n.d.). Hyptis suaveolens (L.) Poit. Plants of the
     World Online. Retrieved from
     https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:448418-1
 
 - Nigeria’s
     medicinal plants: Hyptis suaveolens (Arunfofo). (2019). Punch
     Newspapers. Retrieved from
     https://punchng.com/nigerias-medicinal-plants-hyptis-suaveolens-arunfofo/
 
 - Mesosphaerum
     suaveolens. (n.d.). Wikipedia. Retrieved from https://en.wikipedia.org/wiki/Mesosphaerum_suaveolens
 
 - Mesosphaerum
     suaveolens. (n.d.). NParks Flora & Fauna Web. Retrieved from
     https://www.nparks.gov.sg/florafaunaweb/flora/3/7/3741
 
 - Hyptis
     suaveolens. (n.d.). Key Search. Retrieved from
     https://keyserver.lucidcentral.org/weeds/data/media/Html/mesosphaerum_suaveolens.htm
 
 - Suob
     kabayo (Hyptis suaveolens). (n.d.). StuartXchange. Retrieved from https://www.stuartxchange.com/SuobKabayo.html
 
 - Hyptis
     suaveolens. (n.d.). Useful Tropical Plants. Retrieved from
     https://tropical.theferns.info/viewtropical.php?id=Hyptis+suaveolens
 
 - Hyptis
     suaveolens (L.) Poit. (n.d.). GBIF. Retrieved from
     https://www.gbif.org/species/2926823
 
 - Hyptis
     suaveolens - LAMIACEAE. (n.d.). IDAO CIRAD. Retrieved from
     https://idao.cirad.fr/content/oswald/species/h/hypsu/hypsu_en.html
 
 - An
     ethnopharmacological review of Hyptis suaveolens (L.) Poit. (n.d.). Semantic
     Scholar. Retrieved from
     [https://pdfs.semanticscholar.org/1b60/c1bdede7d9b5e04596bf80d2958832a
 
 External links - https://en.wikipedia.org/wiki/Mesosphaerum_suaveolens
 - https://www.cabidigitallibrary.org/doi/full/10.1079/cabicompendium.110258
 - https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:448418-1
 - https://www.gbif.org/species/2926823
 - https://www.ajol.info/index.php/ajb/article/view/42928
 - https://gd.eppo.int/taxon/HPYSU
 - https://tropical.theferns.info/viewtropical.php?id=Hyptis+suaveolens
 
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