Morin
| Compound Structure: |
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| Synonyms: | Morin; Aurantica; Calico Yellow; 2',3,4',5,7-Pentahydroxyflavone; 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one; Toxylon Pomiferum; Morin hydrate; 3,5,7,2',4'-Pentahydroxyflavone; 3,5,7,2',4'-Pentahydroxyflavonol | ||||||||||||||||||||||||||||||||||||||||||
| Compound ID: | NMPC-1274 | ||||||||||||||||||||||||||||||||||||||||||
| PubChem ID: | |||||||||||||||||||||||||||||||||||||||||||
| Molecular Formula: | C15H10O7 | ||||||||||||||||||||||||||||||||||||||||||
| Canonical SMILES: | C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O | ||||||||||||||||||||||||||||||||||||||||||
| InChIKey: | YXOLAZRVSSWPPT-UHFFFAOYSA-N | ||||||||||||||||||||||||||||||||||||||||||
| About the compound: | Morin is a notable flavonoid compound with various biological activities and applications: Chemical Structure and Sources: Morin is a pentahydroxyflavone, specifically a 7-hydroxyflavonol, with additional hydroxy substituents at positions 2', 4', and 5'. It is a yellow compound that can be isolated from Maclurapomifera (Osage orange), Macluratinctoria (old fustic), and the leaves of Psidiumguajava (common guava). Biological Roles and Health Benefits: Morin acts as an antioxidant, a metabolite, and possesses various health-promoting properties such as being an antihypertensive, hepatoprotective, neuroprotective, anti-inflammatory, antineoplastic, and antibacterial agent. It inhibits DNA topoisomerase (EC 5.99.1.2) and modulates angiogenesis. Morin has been found to be a weak inhibitor of fatty acid synthase and can inhibit amyloid formation by islet amyloid polypeptide, as well as disaggregate amyloid fibers. It exhibits inhibitory action against IgE-mediated allergic responses, particularly in the context of allergic asthma, by down-regulating certain inflammatory markers and cytokines in the lungs. Analytical Uses: Morin is useful in chemical analysis for testing the presence of aluminium or tin in solutions. It forms fluorescent coordination complexes with these metals under UV light, aiding in their detection. The diverse biological activities of morin, ranging from health benefits to its use in analytical chemistry, make it a compound of significant interest in both scientific research and practical applications. Its role in modulating various physiological processes underscores the potential for its use in therapeutic contexts. GHS Hazard Statements • H301 (31.93%): Toxic if swallowed [Danger Acute toxicity, oral] • H302 (48.74%): Harmful if swallowed [Warning Acute toxicity, oral] • H315 (49.58%): Causes skin irritation [Warning Skin corrosion/irritation] • H319 (49.58%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] • H335 (48.74%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] • H341 (46.22%): Suspected of causing genetic defects [Warning Germ cell mutagenicity] • H411 (16.81%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] |
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| Properties: |
Chemical and Physical Properties
Source: PubChem |
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| Source Species: |
Ficus thonningii |