178

Acetamide, also known by its systematic name ethanamide, is an interesting organic compound with the formula CH3CONH2. Here's an overview of its properties, uses, and safety aspects:

Chemical Nature:

Acetamide is derived from acetic acid and is a member of the class of acetamides.

It can be considered a compound intermediate between acetone (which has two methyl groups on either side of a carbonyl group) and urea (which has two amide groups in those positions).

Chemically, it's classified as a monocarboxylic acid amide, a N-acylammonia, and a member of acetamides.

Uses and Applications:

Acetamide finds use as a solvent and a plasticizer in various industrial applications.

It is particularly utilized in the plastics and chemical industries.

Safety and Health Effects:

Acetamide can cause mild skin irritation upon acute (short-term) exposure.

There is limited information available regarding its chronic (long-term), reproductive/developmental, or carcinogenic effects on humans.

As of now, the U.S. Environmental Protection Agency (EPA) has not classified acetamide for carcinogenicity.

Natural Occurrence:

Interestingly, acetamide also occurs naturally as a mineral and is recognized by the IMA symbol: Ace.

Acetamide is a prime example of a chemical that bridges the gap between basic organic compounds and finds utility in specialized industrial applications. However, like many chemicals used in industry, it necessitates careful handling and awareness of potential health impacts, despite the lack of comprehensive data on its long-term effects.

GHS Hazard Statements

H351: Suspected of causing cancer [Warning Carcinogenicity]

First Aid

1. Eyes:

• Remove contact lenses if present.

• Flush the eyes with water or saline for 20-30 minutes while seeking medical advice from a hospital or poison control center.

• Avoid using any ointments, oils, or medication in the eyes unless instructed by a physician.

• Transport the victim to a hospital immediately after flushing, even if no symptoms are evident.

2. Skin:

• Immediately rinse the affected skin with water while removing contaminated clothing.

• Wash the affected areas thoroughly with soap and water.

• Seek medical attention if symptoms like redness or irritation appear, and be prepared to transport the victim to a hospital.

3. Inhalation:

• Leave the contaminated area immediately and breathe fresh air.

• Call a physician and prepare to transport the victim to a hospital, even if no symptoms are present.

• Rescuers should use proper respiratory protection, preferably a Self-Contained Breathing Apparatus (SCBA), when entering an unknown atmosphere.

4. Ingestion:

• Do not induce vomiting.

• If the victim is conscious and not convulsing, give water to dilute the chemical and seek immediate medical advice.

• If the victim is unconscious or convulsing, keep the airway open, position the victim appropriately, and do not give anything by mouth.

• Transport the victim to a hospital immediately.

5. Other Considerations:

• Since the chemical may be carcinogenic, contact a physician for advice on long-term health effects and potential for medical monitoring, which will depend on the specific chemical properties and exposure details.

This guidance is essential for effectively managing chemical exposures and minimizing potential health impacts.

Chemical and Physical Properties

Source: PubChem