Taxifolin

Taxifolin
Compound Structure:
Synonyms: TAXIFOLIN;(+)-Taxifolin;480-18-2;dihydroquercetin;Distylin;Taxifoliol;(+)-Dihydroquercetin;(2R,3R)-Dihydroquercetin;24198-97-8;Lavitol;Diquertin;Lariksin;2,3-Dihydroquercetin;Flamena D;(+/-)-Taxifolin;TAXIFOLIN-(+);17654-26-1;(2R,3R)-3,3',4',5,7-Pentahydr
Compound ID: NMPC-024
PubChem ID:

439533

Molecular Formula: C15H12O7
Canonical SMILES: C1=CC(=C(C=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
InChIKey: CXQWRCVTCMQVQX-LSDHHAIUSA-N
About the compound:

Taxifolin, also known as dihydroquercetin, is structurally similar to the well-known flavonoid quercetin, but has a saturated (not containing double bonds) C2-C3 bond in the C-ring, classifying it as a flavanonol. (+)-taxifolin is a taxifolin that has (2R,3R)-configuration. It has a role as a metabolite. It is a conjugate acid of a (+)-taxifolin(1-). It is an enantiomer of a (-)-taxifolin. Taxifolin is found in a variety of plants. Significant sources include onions, Douglas fir bark, French maritime pine bark, and certain kinds of citrus fruits. Taxifolin exhibits potent antioxidant activity, making it of interest for potential protective effects against diseases linked to oxidative stress. Some studies suggest taxifolin has anti-inflammatory properties, which can be beneficial in conditions associated with inflammation. Anti-cancer: Preliminary research has shown that taxifolin can inhibit the growth of certain cancer cells. Due to its antioxidant properties, taxifolin can be used in skincare products to protect the skin from oxidative damage.

Safety and Hazard

GHS Hazard Statements        

•           H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

Properties:

Chemical and Physical Properties

Property Name

Property Value

Molecular Weight

304.25 g/mol

XLogP3-AA

1.5

Hydrogen Bond Donor Count

5

Hydrogen Bond Acceptor Count

7

Rotatable Bond Count

1

Exact Mass

304.05830272 g/mol

Monoisotopic Mass

304.05830272 g/mol

Topological Polar Surface Area

127Ų

Heavy Atom Count

22

Formal Charge

0

Complexity

428

Isotope Atom Count

0

Defined Atom Stereocenter Count

2

Undefined Atom Stereocenter Count

0

Defined Bond Stereocenter Count

0

Undefined Bond Stereocenter Count

0

Covalently-Bonded Unit Count

1

Compound Is Canonicalized

Yes

Source: PubChem
Source Species: Ficus thonningii
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