Isoprophyl myristate

Isoprophyl myristate
Compound Structure:
Synonyms: propan-2-yl tetradecanoate; Isopropyl tetradecanoate; Estergel; Isomyst; Bisomel; Promyr; Tetradecanoic acid, 1-methylethyl ester; Deltyl Extra; Kesscomir; Tegester; 1-Methylethyl tetradecanoate; Deltylextra; Myristic acid isopropyl ester; Kessco isopropy
Compound ID: NMPC-1164
PubChem ID:

8042

Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
About the compound:

Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.

GHS Hazard Statements

H315 (99.58%): Causes skin irritation [Warning Skin corrosion/irritation]

First Aid

For immediate first aid:

Ensure adequate decontamination.

Perform artificial respiration if not breathing, using appropriate equipment.

Administer CPR if necessary.

Immediately flush contaminated eyes with gently flowing water.

Do not induce vomiting; if vomiting occurs, position patient to prevent aspiration.

Keep patient calm and maintain normal body temperature, seek medical attention.

For basic treatment:

Establish airway, suction if necessary.

Assist ventilation if needed, administer oxygen.

Monitor for pulmonary edema, shock, and seizures, treat as necessary.

Flush eyes immediately with water, irrigate continuously with saline during transport.

Rinse mouth, administer water for ingestion.

Cover skin burns with sterile dressings after decontamination.

For advanced treatment:

Consider intubation for airway control in severe cases.

Use positive-pressure ventilation if beneficial.

Consider drug therapy for pulmonary edema and severe bronchospasm.

Monitor cardiac rhythm, treat arrhythmias.

Start IV fluid administration, monitor for hypovolemia and fluid overload.

Treat seizures with appropriate medication.

Use proparacaine hydrochloride for eye irrigation.

Overall, ensure thorough decontamination, airway management, and seek medical attention promptly.

Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3Rd edition, Elsevier Mosby, St. Louis, MO 2005,

Properties:

Chemical and Physical Properties

Property Name

Property Value

Molecular Weight

270.5 g/mol

XLogP3-AA

7.2

Hydrogen Bond Donor Count

0

Hydrogen Bond Acceptor Count

2

Rotatable Bond Count

14

Exact Mass

270.255880323 g/mol

Monoisotopic Mass

270.255880323 g/mol

Topological Polar Surface Area

26.3²

Heavy Atom Count

19

Formal Charge

0

Complexity

199

Isotope Atom Count

0

Defined Atom Stereocenter Count

0

Undefined Atom Stereocenter Count

0

Defined Bond Stereocenter Count

0

Undefined Bond Stereocenter Count

0

Covalently-Bonded Unit Count

1

Compound Is Canonicalized

Yes

Physical Description

Liquid

Boiling Point

588 K (315 °C) at 760 mm Hg

Melting Point

3 °C

Density

0.847 - 0.855

Solubility 

Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil; practically insoluble in glycerol, propylene glycol

Vapor Pressure

0.0000935 [mmHg]

Source: PubChem        

Source Species: Bryophyllum pinnatum
Piliostigma thonningii.
Plumeria alba
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